AttributeError: 'tuple' object has no attribute 'is_enabled'

You are passing in a tuple to a method that expects an element. From the expected_conditions.staleness_of() documentation:

class selenium.webdriver.support.expected_conditions.staleness_of(element)

Wait until an element is no longer attached to the DOM. element is the element to wait for.

This differs from some of the other expected_conditions convenience methods, which take a locator argument. This particular method can't take a locator, because a locator can only ever find elements that are still attached to the DOM.

Locate the element first before it has been detached:

from selenium.common.exceptions import NoSuchElementException

try:
    element = driver.find_element_by_xpath("//div[@class='loading_icon']")
    WebDriverWait(driver, 10).until(EC.staleness_of(element))
except NoSuchElementException:
    element = None