How to plot in multiple subplots

There are several ways to do it. The subplots method creates the figure along with the subplots that are then stored in the ax array. For example:

import matplotlib.pyplot as plt

x = range(10)
y = range(10)

fig, ax = plt.subplots(nrows=2, ncols=2)

for row in ax:
    for col in row:
        col.plot(x, y)

plt.show()

However, something like this will also work, it's not so "clean" though since you are creating a figure with subplots and then add on top of them:

fig = plt.figure()

plt.subplot(2, 2, 1)
plt.plot(x, y)

plt.subplot(2, 2, 2)
plt.plot(x, y)

plt.subplot(2, 2, 3)
plt.plot(x, y)

plt.subplot(2, 2, 4)
plt.plot(x, y)

plt.show()

import matplotlib.pyplot as plt

fig, ax = plt.subplots(2, 2)

ax[0, 0].plot(range(10), 'r') #row=0, col=0
ax[1, 0].plot(range(10), 'b') #row=1, col=0
ax[0, 1].plot(range(10), 'g') #row=0, col=1
ax[1, 1].plot(range(10), 'k') #row=1, col=1
plt.show()

You might be interested in the fact that as of matplotlib version 2.1 the second code from the question works fine as well.

From the change log:

Figure class now has subplots method The Figure class now has a subplots() method which behaves the same as pyplot.subplots() but on an existing figure.

Example:

import matplotlib.pyplot as plt

fig = plt.figure()
axes = fig.subplots(nrows=2, ncols=2)

plt.show()

Read the documentation: matplotlib.pyplot.subplots

pyplot.subplots() returns a tuple fig, ax which is unpacked in two variables using the notation

fig, axes = plt.subplots(nrows=2, ncols=2)

The code:

fig = plt.figure()
axes = fig.subplots(nrows=2, ncols=2)

does not work because subplots() is a function in pyplot not a member of the object Figure.